Camp^tm2.2Jimw
Targeted Allele Detail

Summary

• Symbol: Camp^tm2.2Jimw
• Name: cathelicidin antimicrobial peptide; targeted mutation 2.2, Ji Ming Wang
• MGI ID: MGI:6150895
• Synonyms: CRAMP^-
• Gene: Camp Location: Chr9:109676445-109678524 bp, - strand Genetic Position: Chr9, 59.8 cM
• Alliance: Camp^tm2.2Jimw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259798
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted downstream to exon 4 and a loxP-frt-flanked Neomycin selection cassette was inserted in intron 3, upstream of exon 4. Cre-mediated recombination removed the neomycin cassette and exon 4. (J:259798)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camp Mutation: 15 strains or lines available

References

• Original: J:259798 Yoshimura T, et al., The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance. J Immunol. 2018 Mar 15;200(6):2174-2185
• All: 1 reference(s)