Tg(Gnat3)28Rfm
Transgene Detail

Summary

• Symbol: Tg(Gnat3)28Rfm
• Name: transgene insertion 28, Robert F Margolskee
• MGI ID: MGI:6150892
• Transgene: Tg(Gnat3)28Rfm Location: unknown
• Alliance: Tg(Gnat3)28Rfm page

Transgene origin

• Strain of Origin: B6CBAF1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Gnat3)28Rfm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Gnat3 (286924)

  Gnat3

  (MGI:3588268)

• Mutation details: An 8.4-kb fragment of the mouse alpha-gustducin gene that drives taste receptor cell-specific expression was cloned 5 to the rat wild type cDNA. Three lines of mice (nos. 28, 47, and 63 were generated. Line 28 was chosen for further analysis because the pattern of alpha-gustducin expression matched or exceeded that of WT. (J:128673)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:128673 Ruiz-Avila L, et al., Dominant loss of responsiveness to sweet and bitter compounds caused by a single mutation in alpha -gustducin. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8868-73
• All: 2 reference(s)