Cd84^tm1.2Cpt
Targeted Allele Detail

Summary

• Symbol: Cd84^tm1.2Cpt
• Name: CD84 antigen; targeted mutation 1.2, Cox Terhorst
• MGI ID: MGI:6149971
• Gene: Cd84 Location: Chr1:171667265-171718285 bp, + strand Genetic Position: Chr1, 79.54 cM
• Alliance: Cd84^tm1.2Cpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260068
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 1. (J:260068)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd84 Mutation: 54 strains or lines available

References

• Original: J:260068 De Calisto J, et al., SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors. Front Immunol. 2014;5:186
• All: 2 reference(s)