Gt(ROSA)26Sor^{tm1(CAG-S1pr1*/tRFP,-S1pr1/EGFP)Srsb}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-S1pr1*/tRFP,-S1pr1/EGFP)Srsb}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Susan R Schwab
• MGI ID: MGI:6149751
• Synonyms: S1PR1^NB-TagRFP S1PR1-eGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-S1pr1*/tRFP,-S1pr1/EGFP)Srsb} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:234057
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into the loci a CAG promoter, floxed STOP cassette, a non-binding S1pr1 with a R120A amino-acid substitution fused to tag RFP (tRFP), a P2A ribosomal skip sequence and S1pr1 fused to EGFP. (J:234057)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1098 strains or lines available

References

• Original: J:234057 Ramos-Perez WD, et al., A map of the distribution of sphingosine 1-phosphate in the spleen. Nat Immunol. 2015 Dec;16(12):1245-52
• All: 3 reference(s)