Arv1^tm1.1Radr
Targeted Allele Detail

Summary

• Symbol: Arv1^tm1.1Radr
• Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1.1, Daniel J Rader
• MGI ID: MGI:6149716
• Gene: Arv1 Location: Chr8:125448878-125460862 bp, + strand Genetic Position: Chr8, 72.81 cM
• Alliance: Arv1^tm1.1Radr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241193
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exons 2 and 3. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:241193)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arv1 Mutation: 15 strains or lines available

References

• Original: J:241193 Lagor WR, et al., Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure. Nutr Diabetes. 2015 Oct 19;5:e181
• All: 1 reference(s)