Foxn1^tm1.1Ghr
Targeted Allele Detail

Summary

• Symbol: Foxn1^tm1.1Ghr
• Name: forkhead box N1; targeted mutation 1.1, Georg A Hollander
• MGI ID: MGI:6149596
• Synonyms: Foxn1^fl
• Gene: Foxn1 Location: Chr11:78248403-78277384 bp, - strand Genetic Position: Chr11, 46.74 cM
• Alliance: Foxn1^tm1.1Ghr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 7 and an FRT flanked pgk-neo cassette and loxP site were inserted downstream of exon 8 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:258932)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxn1 Mutation: 104 strains or lines available

References

• Original: J:258932 Zuklys S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells. Nat Immunol. 2016 Oct;17(10):1206-1215
• All: 1 reference(s)