Lfng^tm1.1Aaul
Targeted Allele Detail

Summary

• Symbol: Lfng^tm1.1Aaul
• Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1.1, Alexander Aulehla
• MGI ID: MGI:6147848
• Synonyms: LfngT2A, Lfng-T2A-VenusPEST, Lfng^{tm1.1(T2AVenusPEST)AAU}
• Gene: Lfng Location: Chr5:140593096-140601300 bp, + strand Genetic Position: Chr5, 79.15 cM
• Alliance: Lfng^tm1.1Aaul page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258120
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: A 2A site, Venus reporter cassette with a destabilized fluorophore, and an FRT and loxP flanked neo cassette were targeted at the stop codon. The selection cassette was removed after targeting. (J:258120)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lfng Mutation: 32 strains or lines available

References

• Original: J:258120 Sonnen KF, et al., Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation. Cell. 2018 Feb 22;172(5):1079-1090.e12
• All: 1 reference(s)