Naip5^tm1Fsha
Targeted Allele Detail

Summary

• Symbol: Naip5^tm1Fsha
• Name: NLR family, apoptosis inhibitory protein 5; targeted mutation 1, Feng Shao
• MGI ID: MGI:6147814
• Gene: Naip5 Location: Chr13:100348247-100382831 bp, - strand Genetic Position: Chr13, 53.05 cM, cytoband D1-D3
• Alliance: Naip5^tm1Fsha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233312
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP-flanked neomycin-coding cassette replaced the largest exon, exon 9, which covers the entire nucleotide-binding oligomerization domain and two leucine-rich repeat units. (J:233312)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Naip5 Mutation: 103 strains or lines available

References

• Original: J:233312 Zhao Y, et al., Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice. J Exp Med. 2016 May 2;213(5):647-56
• All: 1 reference(s)