Cnr2^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Cnr2^tm1Ics
• Name: cannabinoid receptor 2; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:6147781
• Synonyms: CB2^flox
• Gene: Cnr2 Location: Chr4:135622705-135647518 bp, + strand Genetic Position: Chr4, 68.01 cM
• Alliance: Cnr2^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258411
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• The gene was floxed. (J:258411)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cnr2 Mutation: 24 strains or lines available

References

• Original: J:258411 Denaes T, et al., The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway. Sci Rep. 2016 Jun 27;6:28806
• All: 1 reference(s)