Ctnnb1^Rgsc1880
Chemically induced Allele Detail

Summary

• Symbol: Ctnnb1^Rgsc1880
• Name: catenin beta 1; RIKEN Genomic Sciences Center, 1880
• MGI ID: MGI:6147719
• Synonyms: beta-catenin^C429S, Ctnnb1/C429S
• Gene: Ctnnb1 Location: Chr9:120762466-120789573 bp, + strand Genetic Position: Chr9, 72.19 cM
• Alliance: Ctnnb1^Rgsc1880 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Undefined
• Mutation details: The molecular lesion is a T-to-A transverse point mutation that alters codon 429 from one encoding cysteine to one encoding serine. (J:250490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ctnnb1 Mutation: 47 strains or lines available

References

• Original: J:250490 Murata T, et al., beta-CateninC429S mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia. Sci Rep. 2014 Nov 7;4:6959
• All: 1 reference(s)