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Cdh9tm1b(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Cdh9tm1b(KOMP)Wtsi
Name: cadherin 9; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:6147663
Gene: Cdh9  Location: Chr15:16728756-16857094 bp, + strand  Genetic Position: Chr15, 7.91 cM
Mutation
origin
Mutant Cell Line:  EPD0837_1_F03
Germline Transmission:  Earliest citation of germline transmission: J:214586
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 16830456 of Chromosome 15 upstream of exon 5 (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 5 at position 16831352. Exon 5 is thus flanked by loxP sites. After subsequent cre expression this reporter knockout allele was created. (J:214586)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh9 Mutation:  29 strains or lines available
References
Original:  J:214586 Duan X, et al., Type II cadherins guide assembly of a direction-selective retinal circuit. Cell. 2014 Aug 14;158(4):793-807
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory