Del(14)1Tshir
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(14)1Tshir
• Name: deletion, Chr 14, Toshihiko Shiroishi 1
• MGI ID: MGI:6143933
• Synonyms: Del1Tshir, deltaChr14-150k
• Gene: Del(14)1Tshir Location: unknown Genetic Position: Chr14, Syntenic

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Endonuclease-mediated (No functional change)
• Mutation: Intergenic deletion
• Mutation details: CRISPR-targeting removed 150 kb from chromosome 14 (Chr14: 110087232-110237755, GRCm38) that is responsible for the Hm phenotype when inserted into chromosome 5 upstream of Shh. (J:257759)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(14)1Tshir Mutation: 0 strains or lines available

References

• Original: J:257759 Mouri K, et al., Enhancer adoption caused by genomic insertion elicits interdigital Shh expression and syndactyly in mouse. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1021-1026
• All: 1 reference(s)