Rgmb^tm2.1Hlin
Targeted Allele Detail

Summary

• Symbol: Rgmb^tm2.1Hlin
• Name: repulsive guidance molecule family member B; targeted mutation 2.1, Herbert Y Lin
• MGI ID: MGI:6121356
• Synonyms: Rgmb^f
• Gene: Rgmb Location: Chr17:16024923-16051508 bp, - strand Genetic Position: Chr17, 8.96 cM
• Alliance: Rgmb^tm2.1Hlin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232417
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 1 was flanked by loxP sites and FRT-flanked neomycin cassette was inserted downstream of exon 1 before the second loxP site. Flp-mediated recombination removed the neomycin cassette. (J:232417)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgmb Mutation: 13 strains or lines available

References

• Original: J:232417 Meng C, et al., Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice. Biol Reprod. 2016 Apr;94(4):78
• All: 2 reference(s)