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Cdyltm1.1Yuw
Targeted Allele Detail
Nomenclature
Symbol: Cdyltm1.1Yuw
Name: chromodomain protein, Y chromosome-like; targeted mutation 1.1, Yun Wang
MGI ID: MGI:6121103
Synonyms: CdylF
Gene: Cdyl  Location: Chr13:35843816-36058046 bp, + strand  Genetic Position: Chr13, 14.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:251551
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into intron 4 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 5. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exon 5 floxed. (J:251551)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdyl Mutation:  58 strains or lines available
References
Original:  J:251551 Qin R, et al., CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy. Cell Rep. 2017 Jan 10;18(2):380-390
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory