Tg(Lfng-cre/ERT2)1Mmsa
Transgene Detail

Summary

• Symbol: Tg(Lfng-cre/ERT2)1Mmsa
• Name: transgene insertion 1, Mirjana Maletic-Savatic
• MGI ID: MGI:6120527
• Synonyms: Lfng-CreER^T2
• Transgene: Tg(Lfng-cre/ERT2)1Mmsa Location: unknown
• Alliance: Tg(Lfng-cre/ERT2)1Mmsa page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Lfng-cre/ERT2)1Mmsa expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lfng (MGI:1095413)

• Mutation details: A targeting construct containing the cre/ERT2 fusion gene was inserted in front of the transcription start site of the mouse Lfng gene in a BAC (Rp23-270N2). The resulting BAC transgene was microinjected into FVB/n embryos. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:247510)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lfng (mouse) Summary of all recombinase alleles driven by Lfng. Comparative matrix view of recombinase activities Alliance mouse Lfng gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:247510 Semerci F, et al., Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. Elife. 2017 Jul 12;6:e24660
• All: 3 reference(s)