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Tenm3tm1(cre)Luo
Targeted Allele Detail
Nomenclature
Symbol: Tenm3tm1(cre)Luo
Name: teneurin transmembrane protein 3; targeted mutation 1, Liqun Luo
MGI ID: MGI:6120493
Synonyms: Ten3cre
Gene: Tenm3  Location: Chr8:48680717-49296986 bp, - strand  Genetic Position: Chr8, 27.02 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:257337
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6 x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre recombinase, a synthetic intron, woodchuck hepatitis virus post-transcriptional regulatory element (WPRE), bovine growth hormone polyA (bGH pA) and an FRT-flanked PGK-neomycin cassette replace sequences of the mouse Tenm3 gene immediately 3' of the ATG transcriptional start site in exon 1 via homologous recombination in embryonic stem cells. The neomycin cassette was retained.The mutation functions as a Tenm3 null allele lacking protein expression. (J:257337)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tenm3     Summary of all recombinase alleles driven by Tenm3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tenm3 Mutation:  158 strains or lines available
References
Original:  J:257337 Berns DS, et al., Teneurin-3 controls topographic circuit assembly in the hippocampus. Nature. 2018 Feb 15;554(7692):328-333
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory