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Sema3ftm1.1Alk
Targeted Allele Detail
Summary
Symbol: Sema3ftm1.1Alk
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 1.1, Alex L Kolodkin
MGI ID: MGI:6119682
Synonyms: MycSema3F
Gene: Sema3f  Location: Chr9:107558699-107587674 bp, - strand  Genetic Position: Chr9, 58.91 cM, cytoband F2
Alliance: Sema3ftm1.1Alk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:256151
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Epitope tag, No functional change)
Mutation:    Insertion
 
Mutation detailsA 6xMyc epitope tag was inserted in exon 2 adjacent to the C-terminus of the signal sequence between the codons for L26 and L27 and a floxed neo cassette was inserted 510 bp downstream of exon 2 via homologous recombination. Cre-mediated recombination removed the neo cassette. (J:256151)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema3f Mutation:  41 strains or lines available
References
Original:  J:256151 Wang Q, et al., Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons. Neuron. 2017 Dec 6;96(5):1084-1098.e7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory