Kif2a^tm2.2Noh
Targeted Allele Detail

Summary

• Symbol: Kif2a^tm2.2Noh
• Name: kinesin family member 2A; targeted mutation 2.2, Nobutaka Hirokawa
• MGI ID: MGI:6118193
• Synonyms: Kif2a^-
• Gene: Kif2a Location: Chr13:107095504-107158634 bp, - strand Genetic Position: Chr13, 58.06 cM, cytoband F
• Alliance: Kif2a^tm2.2Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256689
• Parent Cell Line: CMTI-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed beta-geo cassette was inserted upstream of exon P and a third loxP site was inserted downstream of exon P+2 via homologous recombination. Cre mediated recombination removed the beta-geo cassette and the three exons. (J:256689)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif2a Mutation: 27 strains or lines available

References

• Original: J:256689 Homma N, et al., KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring. Elife. 2018 Jan 9;7:e30935
• All: 1 reference(s)