Gt(ROSA)26Sor^{tm1(Foxf1)Psta}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Foxf1)Psta}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Pawel Stankiewicz
• MGI ID: MGI:6118052
• Synonyms: R26-LSL-Foxf1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Foxf1)Psta} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237109
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Foxf1)Psta} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Foxf1

• Mutation details: The targeting construct inserted into the locus a floxed PGK-neo STOP cassette (LSL) followed by the Foxf1 cDNA. Upon Cre-induced recombination, the STOP cassette is excised and the cDNA is expressed. (J:237109)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1062 strains or lines available

References

• Original: J:237109 Dharmadhikari AV, et al., Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression. Biol Open. 2016 Nov 15;5(11):1595-1606
• All: 1 reference(s)