Tet3^tm1.1Yts
Targeted Allele Detail

Summary

• Symbol: Tet3^tm1.1Yts
• Name: tet methylcytosine dioxygenase 3; targeted mutation 1.1, Yuichi Tsukada
• MGI ID: MGI:6118043
• Synonyms: Tet3^F
• Gene: Tet3 Location: Chr6:83339355-83434190 bp, - strand Genetic Position: Chr6, 35.94 cM
• Alliance: Tet3^tm1.1Yts page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:248833
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and a FRT flanked PGK-promoter driven neomycin resistance gene and loxP site were inserted downstream of exon 3. Flp-mediated recombination removed the neomycin cassette leaving exon3 floxed. (J:248833)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tet3 Mutation: 60 strains or lines available

References

• Original: J:248833 Tsukada Y, et al., Maternal TET3 is dispensable for embryonic development but is required for neonatal growth. Sci Rep. 2015 Oct 28;5:15876
• All: 4 reference(s)