Atoh8^tm2.1Gasa
Targeted Allele Detail

Summary

• Symbol: Atoh8^tm2.1Gasa
• Name: atonal bHLH transcription factor 8; targeted mutation 2.1, Rosa Gasa
• MGI ID: MGI:6117851
• Synonyms: Atoh8 fl
• Gene: Atoh8 Location: Chr6:72183161-72212561 bp, - strand Genetic Position: Chr6, 32.27 cM
• Alliance: Atoh8^tm2.1Gasa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:248949
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a FRT-flanked PGK-promoter driven neomycin resistance gene and loxP site were inserted downstream of exon 1. Flp-mediated recombination removed the neomycin cassette leaving exon 1 floxed. (J:248949)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh8 Mutation: 7 strains or lines available

References

• Original: J:248949 Ejarque M, et al., Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8). PLoS One. 2016;11(1):e0146273
• All: 1 reference(s)