Kdm6atm2c(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Kdm6atm2c(EUCOMM)Wtsi |
Name: |
lysine (K)-specific demethylase 6A; targeted mutation 2c, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:6117755 |
Gene: |
Kdm6a Location: ChrX:18028814-18146175 bp, + strand Genetic Position: ChrX, 13.45 cM
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Alliance: |
Kdm6atm2c(EUCOMM)Wtsi page
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IMPC: |
Kdm6a gene page |
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Mutant Cell Line: |
EPD0506_3_A01 |
Germline Transmission: |
Earliest citation of germline transmission:
J:155845
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
Vector: L1L2_gt0
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Mutation details: The L1L2_gt0 cassette was inserted at position 18064967 of Chromosome X upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 18065789. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking the critical exon(s).
(J:155845)
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Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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