Trp73^tm1.1Piet
Targeted Allele Detail

Summary

• Symbol: Trp73^tm1.1Piet
• Name: transformation related protein 73; targeted mutation 1.1, Jennifer A Pietenpol
• MGI ID: MGI:6117397
• Synonyms: p73^floxE7-9
• Gene: Trp73 Location: Chr4:154140706-154224332 bp, - strand Genetic Position: Chr4, 83.79 cM
• Alliance: Trp73^tm1.1Piet page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:234561
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 7 and an FRT flanked neomycin resistance gene cassette and loxP site were inserted downstream of exon 9. The neomycin cassette was removed through subsequent Flp-mediated recombination. (J:234561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trp73 Mutation: 47 strains or lines available

References

• Original: J:234561 Marshall CB, et al., p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network. Cell Rep. 2016 Mar 15;14(10):2289-300
• All: 1 reference(s)