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Targeted Allele Detail
Symbol: Cd180tm1c(KOMP)Wtsi
Name: CD180 antigen; targeted mutation 1c, Wellcome Trust Sanger Institute
MGI ID: MGI:6117108
Gene: Cd180  Location: Chr13:102693547-102706631 bp, + strand  Genetic Position: Chr13, 54.92 cM
Mutant Cell Line:  EPD0195_5_D11
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion     Vector: L1L2_Bact_P
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 102704272 of Chromosome 13 upstream of exon 3 (Build GRCm38). The cassette contains an FRT site, lacZ coding sequence, loxP site, human beta-actin promoter controlling a neomycin resistance gene, SV40 polyA, a second FRT site and a second loxP site, was inserted upstream of exon 3. Another loxP site was inserted downstream of exon 3 at position 102706930. Flp-mediated recombination removed the FRT-flanked lacZ neo cassette, leaving exon 3 floxed. Exon 3 encodes the majority of the coding sequence for the gene. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd180 Mutation:  30 strains or lines available
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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