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Cd99l2tm1.2Dvst
Targeted Allele Detail
Nomenclature
Symbol: Cd99l2tm1.2Dvst
Name: CD99 antigen-like 2; targeted mutation 1.2, Dietmar Vestweber
MGI ID: MGI:6117037
Synonyms: CD99L2 Delta
Gene: Cd99l2  Location: ChrX:71420060-71492849 bp, - strand  Genetic Position: ChrX, 36.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193021
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-neo cassette flanked by FRT sites was inserted downstream of the ATG-containing exon 1, and the cassette and exon 1 were flanked by loxP sites. Flp-mediated recombination removed the PGK-neo cassette and cre-mediated recombination deleted exon 1, creating a null allele. Immunoblots confirmed the lack of protein expression from this allele. (J:193021)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd99l2 Mutation:  2 strains or lines available
References
Original:  J:193021 Seelige R, et al., Cutting edge: Endothelial-specific gene ablation of CD99L2 impairs leukocyte extravasation in vivo. J Immunol. 2013 Feb 1;190(3):892-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory