Camk2d^tm1Jhb
Targeted Allele Detail

Summary

• Symbol: Camk2d^tm1Jhb
• Name: calcium/calmodulin-dependent protein kinase II, delta; targeted mutation 1, Joan Heller Brown
• MGI ID: MGI:6116709
• Synonyms: CaMKIIdelta^f
• Gene: Camk2d Location: Chr3:126389951-126639975 bp, + strand Genetic Position: Chr3, 55.97 cM
• Alliance: Camk2d^tm1Jhb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149675
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 9. An FRT-flanked neo cassette with a 5' loxP site was inserted downsteam of exon 11. An adjacent FRT-flanked neo cassette remains intact. (J:149675)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camk2d Mutation: 44 strains or lines available

References

• Original: J:149675 Ling H, et al., Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009 May;119(5):1230-40
• All: 5 reference(s)