Atxn3^{Gt(VICTR48)1Lex}
Gene trapped Allele Detail

Summary

• Symbol: Atxn3^{Gt(VICTR48)1Lex}
• Name: ataxin 3; gene trap mutation 1, Lexicon Genetics
• MGI ID: MGI:6116707
• Gene: Atxn3 Location: Chr12:101885160-101924505 bp, - strand Genetic Position: Chr12, 51.32 cM
• Alliance: Atxn3^{Gt(VICTR48)1Lex} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252036
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: This mutation used an unspecified gene trap containing cell line from Lexicon Genetics. The gene trap vector, VICTR48, was inserted in the first intron downstream of the ATG. There is no detectable Atxn3 mRNA or protein in the homozygous mice. (J:252036)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atxn3 Mutation: 48 strains or lines available

References

• Original: J:252036 Reina CP, et al., Basal and stress-induced Hsp70 are modulated by ataxin-3. Cell Stress Chaperones. 2012 Nov;17(6):729-42
• All: 7 reference(s)