Lamtor1^tm2Moka
Targeted Allele Detail

Summary

• Symbol: Lamtor1^tm2Moka
• Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1; targeted mutation 2, Masato Okada
• MGI ID: MGI:6116522
• Synonyms: p18^fl
• Gene: Lamtor1 Location: Chr7:101555044-101561110 bp, + strand Genetic Position: Chr7, 54.68 cM, cytoband F1
• Alliance: Lamtor1^tm2Moka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254130
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were introduced into the 5 and 3 sides of exon 1 of the p18 gene by homologous recombination. (J:254130)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lamtor1 Mutation: 21 strains or lines available

References

• Original: J:254130 Soma-Nagae T, et al., The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes. J Cell Sci. 2013 Aug 15;126(Pt 16):3575-84
• All: 5 reference(s)