Rb1^m3Tno
Chemically induced Allele Detail

Summary

• Symbol: Rb1^m3Tno
• Name: RB transcriptional corepressor 1; mutation 3, Tetsuo Noda
• MGI ID: MGI:6116517
• Synonyms: M1033 line
• Gene: Rb1 Location: Chr14:73430298-73563446 bp, - strand Genetic Position: Chr14, 38.73 cM, cytoband D3
• Alliance: Rb1^m3Tno page

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• The mutation is a A to G mutation in intron 10 at a splice donor site. (J:250068)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rb1 Mutation: 107 strains or lines available

References

• Original: J:250068 Toki H, et al., Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors. Cancer Sci. 2014 Oct;105(10):1360-8
• All: 1 reference(s)