Emx2^tm1.1Ddmo
Targeted Allele Detail

Summary

• Symbol: Emx2^tm1.1Ddmo
• Name: empty spiracles homeobox 2; targeted mutation 1.1, Dennis D M OLeary
• MGI ID: MGI:6116224
• Synonyms: Emx2^fl
• Gene: Emx2 Location: Chr19:59447122-59453789 bp, + strand Genetic Position: Chr19, 56.28 cM
• Alliance: Emx2^tm1.1Ddmo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256576
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the transcriptional start site and a second loxP site was inserted downstream of exon 2. An FRT-site-flanked PGK-Neo cassette inserted adjacent to the second loxP site, and was removed via FLP-mediated recombination. (J:256576)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Emx2 Mutation: 23 strains or lines available

References

• Original: J:256576 Zembrzycki A, et al., Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas. Elife. 2015 Dec 24;4:e11416
• All: 3 reference(s)