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Targeted Allele Detail
Symbol: Chd8tm1.2Mabn
Name: chromodomain helicase DNA binding protein 8; targeted mutaiton 1.2, Michiel A Bassoon
MGI ID: MGI:6115344
Gene: Chd8  Location: Chr14:52435608-52495237 bp, - strand  Genetic Position: Chr14, 26.84 cM
Germline Transmission:  Earliest citation of germline transmission: J:261980
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 3 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed exon 3. (J:261980)
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chd8 Mutation:  67 strains or lines available
Original:  J:261980 Suetterlin P, et al., Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice. Cereb Cortex. 2018 Jun 1;28(6):2192-2206
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory