Sostdc1^tm1Krum
Targeted Allele Detail

Summary

• Symbol: Sostdc1^tm1Krum
• Name: sclerostin domain containing 1; targeted mutation 1, Robb Krumlauf
• MGI ID: MGI:6115338
• Synonyms: Wise^-
• Gene: Sostdc1 Location: Chr12:36364168-36368451 bp, + strand Genetic Position: Chr12, 16.82 cM, cytoband B2
• Alliance: Sostdc1^tm1Krum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168361
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: This mutation was generated by knock-in of a selection cassette into the first exon of the gene. No further details are provided. (J:168361)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sostdc1 Mutation: 28 strains or lines available

References

• Original: J:168361 Ahn Y, et al., Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning. Development. 2010 Oct;137(19):3221-31
• All: 6 reference(s)