Card11^M5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Card11^M5Btlr
• Name: caspase recruitment domain family, member 11; mutation 5, Bruce Beutler
• MGI ID: MGI:6113551
• Synonyms: Tumnus
• Gene: Card11 Location: Chr5:140858745-140986337 bp, - strand Genetic Position: Chr5, 79.42 cM
• Alliance: Card11^M5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 140,885,945 (v38) on chromosome 5, or base pair 114,652 in the GenBank genomic region NC_000071. The mutation corresponds to residue 2,321 in the mRNA sequence NM_175362 within exon 16 of 25 total exons. The mutation results in a glutamine (Q) to arginine (R) substitution at position 667 (Q667R) in the protein. (J:254879)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card11 Mutation: 58 strains or lines available

References

• Original: J:254879 Zhong X, et al., Mutagenetix entry for Tumnus. MGI Direct Data Submission. 2018
• All: 1 reference(s)