Kiss1tm2(cre/GFP)Coll
Targeted Allele Detail
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Symbol: |
Kiss1tm2(cre/GFP)Coll |
Name: |
KiSS-1 metastasis-suppressor; targeted mutation 2, William H Colledge |
MGI ID: |
MGI:6113450 |
Synonyms: |
Kiss1-Cre:GFP, Kiss1CRE-GFP, Kiss1tm2(Cre-GFP)Coll |
Gene: |
Kiss1 Location: Chr1:133254950-133257460 bp, + strand Genetic Position: Chr1, 57.91 cM
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Alliance: |
Kiss1tm2(cre/GFP)Coll page
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Germline Transmission: |
Earliest citation of germline transmission:
J:254977
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Parent Cell Line: |
CCB (ES Cell)
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Strain of Origin: |
129S/SvEv-Gpi1c
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Allele Type: |
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Targeted (Null/knockout, Recombinase, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Kiss1tm2(cre/GFP)Coll expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A targeting vector was designed to insert the cre/GFP fusion gene with a neo cassette in exon 2 of the mouse Kiss1 gene such that ATG of the cre/GFP fusion gene was kept in frame located 11 codons downstream of the Kiss1 ATG. The absence of protein was confirmed in mutant mice.
(J:254977)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Kiss1
(mouse)
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Original: |
J:254977 Yeo SH, et al., Visualisation of Kiss1 Neurone Distribution Using a Kiss1-CRE Transgenic Mouse. J Neuroendocrinol. 2016 Nov;28(11) |
All: |
14 reference(s) |
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