Rr44^em2Axvi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr44^em2Axvi
• Name: regulatory region 44; endonuclease-mediated mutation 2, Axel Visel
• MGI ID: MGI:6113296
• Synonyms: hs122/hs123
• Gene: Rr44 Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Rr44^em2Axvi page

Mutation origin

• Strain of Origin: FVB

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region, Null/knockout)
• Mutation: Intergenic deletion
• Mutation details: CRISPR targeting deleted 1157 bp (chrX:92,790,231-92,791,387; mm10) containing the Arx enhancer in zygotes carrying the Rr43^em1Axvi allele (deletion of another Arx enhancer). (J:254531)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr44 Mutation: 2 strains or lines available

References

• Original: J:254531 Dickel DE, et al., Ultraconserved Enhancers Are Required for Normal Development. Cell. 2018 Jan 25;172(3):491-499.e15
• All: 1 reference(s)