Gt(ROSA)26Sor^{tm3(Irf4)Evdr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm3(Irf4)Evdr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Evan Rosen
• MGI ID: MGI:6112016
• Synonyms: Rosa26-LSL-IRF4
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm3(Irf4)Evdr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214637
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into the locus a floxed STOP cassette, the expressed cDNA, autocleavable viral 2A sequence and an in frame to an N terminus biotin ligase recognition peptide (birA). (J:214637)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:214637 Kong X, et al., IRF4 is a key thermogenic transcriptional partner of PGC-1alpha. Cell. 2014 Jul 3;158(1):69-83
• All: 4 reference(s)