About   Help   FAQ
Snx10em1Ael
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Snx10em1Ael
Name: sorting nexin 10; endonuclease-mediated mutation 1, Ari Elson
MGI ID: MGI:6111480
Gene: Snx10  Location: Chr6:51523901-51590679 bp, + strand  Genetic Position: Chr6, 24.95 cM, cytoband B3
Mutation
origin
Strain of Origin:  C57BL/6JOlaHsd
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsCRISPR targeting introduced a G to A point mutation in exon 4 that results in the amino acid substitution of glutamine for arginine at position 51 (R51Q). (J:289051)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Snx10 Mutation:  137 strains or lines available
References
Original:  J:289051 Stein M, et al., Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice. Bone. 2020 Jul;136:115360
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/16/2021
MGI 6.16
The Jackson Laboratory