Slc17a7^tm1.1Sse
Targeted Allele Detail

Summary

• Symbol: Slc17a7^tm1.1Sse
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; targeted mutation 1.1 Susumu Seino
• MGI ID: MGI:6111444
• Synonyms: VGLUT1-flox
• Gene: Slc17a7 Location: Chr7:44813373-44825566 bp, + strand Genetic Position: Chr7, 29.16 cM
• Alliance: Slc17a7^tm1.1Sse page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250360
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Two loxP sites flank exon 2, which encodes the first transmembrane domain. An Frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:250360)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc17a7 Mutation: 39 strains or lines available

References

• Original: J:250360 Murao N, et al., Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in beta-cell glutamate signaling for incretin-induced insulin secretion. PLoS One. 2017;12(11):e0187213
• All: 1 reference(s)