Myo9a^tm1.1Bah
Targeted Allele Detail

Summary

• Symbol: Myo9a^tm1.1Bah
• Name: myosin IXa; targeted mutation 1.1, Martin Bahler
• MGI ID: MGI:6111330
• Gene: Myo9a Location: Chr9:59658179-59836149 bp, + strand Genetic Position: Chr9, 32.13 cM
• Alliance: Myo9a^tm1.1Bah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251454
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 2, which includes part of the 5' UTR and codes for the N-terminal 280 of 2542 amino acids of the protein. An adjacent FRT site flanked neomycin selection cassette was removed via Flp-mediated recombination in mice. (J:251454)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo9a Mutation: 114 strains or lines available

References

• Original: J:251454 Abouhamed M, et al., Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus. Mol Biol Cell. 2009 Dec;20(24):5074-85
• All: 1 reference(s)