Opn1mw^em1Sarno
Endonuclease-mediated Allele Detail

Summary

• Symbol: Opn1mw^em1Sarno
• Name: opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan); endonuclease-mediated mutation 1, Renata Sarno
• MGI ID: MGI:6108875
• Synonyms: Opn1mw^C198R
• Gene: Opn1mw Location: ChrX:73171072-73194362 bp, + strand Genetic Position: ChrX, Syntenic
• Alliance: Opn1mw^em1Sarno page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: Plasmids encoding a signal guide RNA are designed to insert a point mutation in exon 4 of the gene. Exon 4 was modified to harbor a tyrosine to cytosine substitution at amino acid 198 (C198R), which corresponds to a C203R mutation commonly found in patients with Blue Cone Monochromacy. (J:101977)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Opn1mw Mutation: 5 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 3 reference(s)