Nlrp9b^em2Flv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nlrp9b^em2Flv
• Name: NLR family, pyrin domain containing 9B; endonuclease-mediated mutation 2, Richard Flavell
• MGI ID: MGI:6106861
• Synonyms: Flag Nlrp9 KI
• Gene: Nlrp9b Location: Chr7:19725318-19796867 bp, + strand Genetic Position: Chr7, 9.96 cM
• Alliance: Nlrp9b^em2Flv page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: Flag tag sequence was inserted after the ATG translation start site in exon 2, using CRISPR/Cas9 technology. (J:243487)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp9b Mutation: 51 strains or lines available

References

• Original: J:243487 Zhu S, et al., Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. 2017 Jun 29;546(7660):667-670
• All: 1 reference(s)