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Tg(Acta2-cre)1Rkl
Transgene Detail
Nomenclature
Symbol: Tg(Acta2-cre)1Rkl
Name: transgene insertion 1, Raghu Kalluri
MGI ID: MGI:6101504
Synonyms: aSMA-Cre
Transgene: Tg(Acta2-cre)1Rkl  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe aSMA-cre transgenic construct containing the Cre recombinase gene under control of an extended 5.2kb mouse Acta2 (actin, alpha 2, smooth muscle, aorta) gene promoter that includes the Acta2 promoter plus exon 1, intron 1, and part of exon 2, was microinjected into FVB fertilized mouse eggs. The founder line 1 was subsequently established. (J:101977, J:200001)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acta2     Summary of all recombinase alleles driven by Acta2. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:200001 Lebleu VS, et al., Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013 Aug;19(8):1047-53
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory