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Tg(Acta2-TK*)1Rkl
Transgene Detail
Nomenclature
Symbol: Tg(Acta2-TK*)1Rkl
Name: transgene insertion 1, Raghu Kalluri
MGI ID: MGI:6101475
Synonyms: alphaSMA-tk
Transgene: Tg(Acta2-TK*)1Rkl  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgenic construct contains a truncated herpes simplex 1 virus thymidine kinase gene under control of an extended 5.2kb mouse Acta2 gene promoter that includes the Acta2 promoter plus exon 1, intron 1, and part of exon 2. (J:200001)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:200001 Lebleu VS, et al., Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013 Aug;19(8):1047-53
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory