Cdca5^tm1.1Jmpt
Targeted Allele Detail

Summary

• Symbol: Cdca5^tm1.1Jmpt
• Name: cell division cycle associated 5; targeted mutation 1, Jan-Michael Peters
• MGI ID: MGI:6100920
• Synonyms: Cdca5 flx
• Gene: Cdca5 Location: Chr19:6135127-6141803 bp, + strand Genetic Position: Chr19, 4.34 cM
• Alliance: Cdca5^tm1.1Jmpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231691
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A conditional allele was generated by flanking exons 5 and 6 of the gene with loxP sites. An frt-flanked neomycin selection cassette was deleted via FLP-mediated recombination. (J:231691)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdca5 Mutation: 13 strains or lines available

References

• Original: J:231691 Ladurner R, et al., Sororin actively maintains sister chromatid cohesion. EMBO J. 2016 Mar 15;35(6):635-53
• All: 1 reference(s)