Frmd4b^Tvrm222
Chemically induced Allele Detail

Summary

• Symbol: Frmd4b^Tvrm222
• Name: FERM domain containing 4B; translational vision research model 222
• MGI ID: MGI:5912311
• Synonyms: Tvrm222
• Gene: Frmd4b Location: Chr6:97263828-97594502 bp, - strand Genetic Position: Chr6, 44.93 cM
• Alliance: Frmd4b^Tvrm222 page

Mutation origin

• Strain of Origin: B6.Cg-Nr2e3^rd7/J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: The mutation is identified as a T to C transition at nucleotide 2812 and results in a serine to proline substitution at amino acid 938 (S938P). (J:263912)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Frmd4b Mutation: 71 strains or lines available

References

• Original: J:263912 Kong Y, et al., A FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency. Hum Mol Genet. 2018 Jun 27
• All: 1 reference(s)