Pagr1a^tm2.1Kaig
Targeted Allele Detail

Summary

• Symbol: Pagr1a^tm2.1Kaig
• Name: PAXIP1 associated glutamate rich protein 1A; targeted mutation 2.1, Kai Ge
• MGI ID: MGI:5911872
• Synonyms: PA1^flox, Pagr1^lox
• Gene: Pagr1a Location: Chr7:126614223-126616524 bp, - strand Genetic Position: Chr7, 69.27 cM, cytoband F4
• Alliance: Pagr1a^tm2.1Kaig page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:295426
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed neomycin resistance cassette was inserted downstream of exon 2. Cre-mediated recombination removed the selection cassette and left exons 1 and 2 floxed. (J:295426)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pagr1a Mutation: 13 strains or lines available

References

• Original: J:295426 Lee JE, et al., MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPbeta and C/EBPdelta. Mol Cell Biol. 2020 Aug 14;40(17)
• All: 3 reference(s)