Efna5^tm1.1Dcg
Targeted Allele Detail

Summary

• Symbol: Efna5^tm1.1Dcg
• Name: ephrin A5; targeted mutation 1.1, Denis C Guttridge
• MGI ID: MGI:5911674
• Synonyms: Efna5^fl, Efna5^tm1c
• Gene: Efna5 Location: Chr17:62911179-63188312 bp, - strand Genetic Position: Chr17, 32.57 cM
• Alliance: Efna5^tm1.1Dcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229094
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A targeting vector from the International Mouse Knockout Consortium (IKMC) containing an FRT site, IRES-LacZ, loxP site, neo cassette, FRT site, LoxP site, sequence encoding exon 2, and a loxP site was inserted via homologous recombination. Flp-mediated recombination removed the LacZ and neo cassettes leaving exon 2 floxed. (J:229094)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efna5 Mutation: 27 strains or lines available

References

• Original: J:229094 Gu JM, et al., An NF-kappaB - EphrinA5-Dependent Communication between NG2(+) Interstitial Cells and Myoblasts Promotes Muscle Growth in Neonates. Dev Cell. 2016 Jan 25;36(2):215-24
• All: 1 reference(s)