Tll2^tm1.2Sjl
Targeted Allele Detail

Summary

• Symbol: Tll2^tm1.2Sjl
• Name: tolloid-like 2; targeted mutation 1.2, Se-Jin Lee
• MGI ID: MGI:5910879
• Gene: Tll2 Location: Chr19:41071192-41195274 bp, - strand Genetic Position: Chr19, 34.39 cM
• Alliance: Tll2^tm1.2Sjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132807
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A floxed neomycin resistance cassette was inserted downstream of exon 7 and an additional loxP site was inserted upstream of exon 7, then subsequent cre exision removed only the neomycin selection cassette yielding this conditional ready allele. (J:132807)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tll2 Mutation: 55 strains or lines available

References

• Original: J:132807 Lee SJ, Genetic analysis of the role of proteolysis in the activation of latent myostatin. PLoS One. 2008;3(2):e1628
• All: 1 reference(s)