Folh1^tm1.1Jtc
Targeted Allele Detail

Summary

• Symbol: Folh1^tm1.1Jtc
• Name: folate hydrolase 1; targeted mutation 1.1, Joseph T Coyle
• MGI ID: MGI:5909311
• Synonyms: GCP II^-
• Gene: Folh1 Location: Chr7:86368185-86425151 bp, - strand Genetic Position: Chr7, 48.51 cM, cytoband D1-D2
• Alliance: Folh1^tm1.1Jtc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243629
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a loxP site flanked neomycin resistance gene cassette was inserted into intron 2. Exons 1 and 2 and the neo cassette were deleted through subsequent cre-mediated recombination. (J:243629)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Folh1 Mutation: 50 strains or lines available

References

• Original: J:243629 Han L, et al., Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II. Synapse. 2009 Aug;63(8):625-35
• All: 2 reference(s)