Slc32a1^tm2Yyan
Targeted Allele Detail

Summary

• Symbol: Slc32a1^tm2Yyan
• Name: solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 2, Yuchio Yanagawa
• MGI ID: MGI:5909288
• Synonyms: VGAT^floxneo
• Gene: Slc32a1 Location: Chr2:158452687-158457668 bp, + strand Genetic Position: Chr2, 78.72 cM, cytoband H1-3
• Alliance: Slc32a1^tm2Yyan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241759
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. This creates a conditional-ready allele with exons 2 and 3 floxed. (J:241759)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc32a1 Mutation: 55 strains or lines available

References

• Original: J:241759 Saito K, et al., The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice. Mol Brain. 2010 Dec 30;3:40
• All: 3 reference(s)